Hepatitis C treatment is to cure

Had previously heard of viral hepatitis , liver function in patients with high and low , all over seeking doctors, even taking the expensive Chinese and Western medicine , it seems null and void . Watched from hepatitis , cirrhosis to liver cancer , how many friends and family away from us . Since the virus and rapid development of genomics since chronic hepatitis C has been considered incurable diseases.
Taipei City Hospital Yang Hospital District medical director said that , C-type hepatitis infection may be due to blood transfusion or blood contact with infected body fluids , in the past due to post-transfusion infection ratio of about 10 to 15% , but in the routine screening of blood donors detection of hepatitis C virus antibodies has been substantially reduced . Most are sporadic infections, such as intravenous drug users , the use of non- disposable needles to inject , hospital colleagues and family members of patients with chronic hepatitis C or sexual partners , more opportunistic infections . In Taiwan, the general public in the blood of hepatitis C virus antibody positive rate of about 2 to 4%, but the high prevalence areas up to 40 to 60%.
The natural history of viral infection , according to route of infection , the virus characteristics , clinical symptoms and different immune responses in patients . Generally, infection, young, female, nonwhite , less exposure to the virus , such as the immune response is good, as well as in patients with clinical symptoms , and less progress to chronic hepatitis, however , infection with genotype first type of immune dysfunction of the patients progressed to higher rates of chronic hepatitis .
Get acute hepatitis C natural clearance rate, caused by the transfusion of approximately 15 to 25 % of sporadic about 30 to 53 percent , and its duration can be to no active chronic hepatitis and liver function repeatedly to the level of performance of patients with chronic hepatitis . Not active chronic hepatitis patients required to detect hepatitis C viral load , and even liver biopsy assess fibrosis and, if more than the first phase of fibrosis should be considered for treatment , no fibrosis , clinical observations can be. As liver function in patients with chronic hepatitis high and low volatility , the current evidence-based medicine that such treatment is successful, there are 75 to 80% can be cured , it should be considered active treatment.
In general , genotype 1 and 4 type on with a combination of interferon -based antiviral drugs less effective . Therefore, patients should be checked before treatment would face treatment tolerance , liver disease severity , the number concentration of the virus , genotype and treatment if there are some viruses or biochemical reactions - in the fourth week of rapid viral response measurements , such as no or almost no virus volume , and in twelve weeks time also undetectable viral load , only 24 weeks of treatment can be, but the amount of virus in the twelfth week if not less than 100 times the pre-treatment viral load ( representing a decline of 2 logs), will consider withdrawal, but decreased 2 logs , they will have to treat a total of 48 weeks . Patients as smoothly throughout the course of treatment , the final amount of virus to be detected again , and the amount of tracking the virus every six months , at least 2 to 3 times None of the above , be considered cured.